El-Hariry, ImanPowles, ThomasLau, Mike RSternberg, Cora NRavaud, AlainVon der Maase, HansZantl, NikoHarper, PeterRolland, FrédéricAudhuy, BrunoBarthel, FriederikeMachiels, Jean-PascalPatel, PinaKreuser, Ernst-DietrickHawkins, Robert E2010-08-102010-08-102010-03Amplification of epidermal growth factor receptor gene in renal cell carcinoma. 2010, 46 (5):859-62 Eur J Cancer1879-08522016747610.1016/j.ejca.2010.01.011http://hdl.handle.net/10541/109415Expression of epidermal growth factor receptor (EGFR) may be of prognostic value in renal cell cancer (RCC). Gene amplification of EGFR was investigated in a cohort of 315 patients with advanced RCC from a previously reported randomised study. Using fluorescent in situ hybridisation, only 2 patients (0.6%) had gene amplification; therefore gene amplification is of no prognostic value in RCC.enCancerous Gene Expression RegulationAdultAgedAged, 80 and overCarcinoma, Renal CellFemaleGene AmplificationGene Expression Regulation, NeoplasticHumansIn Situ Hybridization, FluorescenceKidney NeoplasmsMaleMiddle AgedPrognosisProspective StudiesReceptor, Epidermal Growth FactorSurvival AnalysisArticleEuropean Journal of Cancer