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NEXUS-01, a phase 1 study of LY4052031, an antibody-drug conjugate targeting nectin-4 in participants with advanced or metastatic urothelial carcinoma or other solid tumors

Gao, X.
; 
Patnaik, A.
; 
Lakhani, N. J.
; 
Call, J. A.
; 
Galsky, M. D.
; 
Garmezy, B.
; 
Wei, A. Z.
; 
Carter, L.
; 
Powles, T.
; 
Siefker-Radtke, A. O.
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Abstract
Authors
Gao, X.
Patnaik, A.
Lakhani, N. J.
Call, J. A.
Galsky, M. D.
Garmezy, B.
Wei, A. Z.
Carter, L.
Powles, T.
Siefker-Radtke, A. O.
O'Donnell, P. H.
Kitano, S.
Castellano, D.
Shinde, R.
Joshua, A. M.
Balbas, M.
Han, H. M.
Chang, A. E.
Baldini, C.
Iyer, G.
Affiliation
Massachusetts Gen Hosp, Canc Ctr, Boston, MA USA START Ctr Canc Res San Antonio, San Antonio, TX USA START Ctr Canc Res, Grand Rapids, MI USA START Ctr Canc Res, Salt Lake City, UT USA Icahn Sch Med Mt Sinai, Tisch Canc Inst, Div Hematol & Oncol, Genitourinary Med Oncol, New York, NY USA Sarah Cannon Res Inst, Nashville, TN USA Columbia Univ, Med Ctr, Dept Med, New York, NY USA Univ Manchester, Div Canc Sci, Manchester, England Christie NHS Fdn Trust, Manchester, England Queen Mary Univ London, Barts Canc Inst, London, England Univ Texas MD Anderson Canc Ctr, Dept Med, Houston, TX USA Univ Chicago, Dept Med, Sect Hematol Oncol, Chicago, IL USA Japanese Fdn Canc Res, Canc Inst Hosp, Dept Adv Med Dev, Tokyo, Japan Hosp Univ 12 Octubre, Med Oncol Serv, Madrid, Spain Linear Clin Res, Nedlands, WA, Australia St Vincents Hosp, Melbourne, Vic, Australia Eli Lilly & Co, Indianapolis, IN USA Gustave Roussy, Drug Dev Dept, Villejuif, France Mem Sloan Kettering Canc Ctr, Dept Med, New York, NY USA
Description
Date
2025
Publisher
Collections
All Christie Publications
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Keywords
Type
Meetings and Proceedings
Citation
Gao X, Patnaik A, Lakhani NJ, Call JA, Galsky MD, Garmezy B, et al. NEXUS-01, a phase 1 study of LY4052031, an antibody-drug conjugate targeting Nectin-4 in participants with advanced or metastatic urothelial carcinoma or other solid tumors. JOURNAL OF CLINICAL ONCOLOGY. 2025 FEB 10;43(5_SUPPL):TPS900-TPS. PubMed PMID: WOS:001454666200012. English.
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URI
https://christie.openrepository.com/handle/10541/627929
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