Acute oncology: the care of older patients in the emergency department
den Duijn, J. Nickel, C. H. Cooksley, T.
den Duijn, J.
Nickel, C. H.
Cooksley, T.
Abstract
PURPOSE OF REVIEW: There has been a notable rise in cancer-related emergencies, especially in older patients, due to an increase in those undergoing complex therapies. In this review, we consider the management and clinical workup of the older cancer patient in the emergency department (ED). We will reflect on clinical features of older patients with cancer, as well as fall, delirium, febrile neutropenia (FN), and immune checkpoint inhibitor toxicity. RECENT FINDINGS: Older patients with cancer are more likely to require admission to hospital following ED attendance. The most common emergency presentations are fever, pain and gastrointestinal symptoms. The complexity of common presentations, such as falls and delirium, is often overlooked in older cancer patients. FN in older patients is associated with increased mortality and a higher likelihood of requiring inpatient care. Despite their therapeutic benefits in older patients, the broad spectrum of immune-related toxicities even at lower grades, can lead to functional decline and the need to discontinue therapy. SUMMARY: The number of older people with cancer presenting to emergency care is expected to rise. In response to this growing and complex demand, a comprehensive, individualised, and multi-disciplinary approach is essential. Clinicians need to be aware of the increasingly broad spectrum of diagnoses in this population and tailor their assessment and management strategies accordingly.
Authors
Description
Date
2026
Publisher
Collections
Keywords
Type
Article
Citation
den Duijn J, Nickel CH, Cooksley T. Acute oncology: the care of older patients in the emergency department. Current Opinion in Supportive and Palliative Care. 2026 Mar 1;20(1):11-7. Epub 2025/12/24.