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Current issues of next-generation sequencing-based circulating tumor DNA analysis in colorectal cancer

Rathnasamy, N.
; 
Lavingia, V.
; 
Aggarwal, S.
; 
Talwar, V.
; 
Shukla, P.
; 
Rohtagi, N.
; 
Prathasarathy, K. M.
; 
Gupta, D.
; 
Pasricha, R.
; 
Pasricha, S.
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Abstract
Evidence is mounting that circulating tumor deoxyribonucleic acid can be tested accurately, frequently, and in a noninvasive form. Its role in monitoring patients with cancer, particularly colorectal cancer, is increasing. In this brief review, we discuss its current role when measured using next-generation sequencing-based methods.
Authors
Rathnasamy, N.
Lavingia, V.
Aggarwal, S.
Talwar, V.
Shukla, P.
Rohtagi, N.
Prathasarathy, K. M.
Gupta, D.
Pasricha, R.
Pasricha, S.
Choudhary, R. K.
Goyal, G.
Rawat, S.
Parikh, P. M.
Selvasekar, C.
Affiliation
Department of Medical Oncology, Royal Care Superspeciality Hospital, Coimbatore, Tamil Nadu, India. Department of Medical Oncology, Shalby Hospital, Ahmedabad, Gujarat, India. Department of Medical Oncology, Sir Ganga Ram Hospital, New Delhi, India. Department of Medical Oncology, Rajiv Gandhi Cancer Institute and Research Center (RGCI), New Delhi, India. Department of Radiation Oncology, Delhi State Cancer Institute, New Delhi, India. Department of Medical Oncology, Fortis Memorial Research Institute (FMRI), New Delhi, India. Department of Medical Oncology, Dharmashila NH Hospital, New Delhi, India. Department of Radiation Oncology, All India Institute of Medical Sciences (AIIMS), Hrishikesh, Hrishikesh, Uttarakhand, India. Department of Pathology, Rajiv Gandhi Cancer Institute and Research Center (RGCI), New Delhi, India. Department of Medical Oncology, Metro Hospital and Cancer Institute, New Delhi, India. Department of Medical Oncology, Max Superspeciality Hospital, Chandigarh, Punjab, India. Department of Surgical Gastroenterology, Sir Ganga Ram Hospital, New Delhi, India. Department of Clinical Hematology, Sri Ram Cancer Center, Mahatma Gandhi University of Medical Sciences and Technology, Jaipur, Rajasthan, India. Clinical Services and Specialist Surgery, The Christie NHS Foundation Trust, Manchester, United Kingdom.
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2024
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All Christie Publications
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Rathnasamy N, Lavingia V, Aggarwal S, Talwar V, Shukla P, Rohtagi N, et al. Current Issues of Next-Generation Sequencing-Based Circulating Tumor DNA Analysis in Colorectal Cancer. South Asian J Cancer. 2024 Oct;13(4):241-5. PubMed PMID: 40060356. Pubmed Central PMCID: PMC11888803. Epub 2025/03/10. eng.
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https://christie.openrepository.com/handle/10541/627631
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