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Development of the SCNS-TARGET: a new tool to assess unmet needs in cancer patients utilising immuno-, biological or precision therapies
Crowe, L. Brown, M. C. Lecouturier, J. Greystoke, A. Nuryunarsih, D. Rimmer, B. Bojke, A. Bojke, R. Richardson, J. Wells, M.
Crowe, L.
Brown, M. C.
Lecouturier, J.
Greystoke, A.
Nuryunarsih, D.
Rimmer, B.
Bojke, A.
Bojke, R.
Richardson, J.
Wells, M.
Abstract
PURPOSE: Develop an instrument to assess unmet needs in cancer patients using immuno-, biological and precision (IBP) therapies. METHODS: Development followed COSMIN guidance. Instruments to assess unmet needs of advanced cancer patients were identified, and quality and content were evaluated in a systematic review (Phase 1). Semi-structured interviews with patients utilising IBP therapies (n = 31) and healthcare professionals (n = 22) explored supportive care needs (Phase 2). Phase 3 selected a base instrument to adapt, generated new items and iteratively refined these through six meetings involving professionals (n = 8) and public and patient involvement representatives (n = 9) and patient cognitive interviews (n = 16). Phase 4 piloted the new instrument (n = 50 patients). RESULTS: Twenty-four instruments were identified; none was developed for patients utilising IBP therapies (Phase 1). Ten domains of unmet needs were identified from the interview data (Phase 2). SCNS-SF34 was selected as the base instrument. Informed by interview data, an 'add-on module' (SCNS-TARGET) was developed for patients utilising IBP therapies comprising 25 questions (psychological domain, 7 items; information, 6; healthcare, 5; economic, 3; role, 2; physical, 1; social, 1; Phase 3). Levels of missingness were low; reliability varied across questions, and, on average, patients reported 7.40 (standard deviation = 8.43) unmet needs on SCNS-TARGET (Phase 4). CONCLUSIONS: SCNS-TARGET is designed for use alongside SCNS-SF34 to assess unmet needs in those using IBP therapies. Content and face validity have been established. IMPLICATIONS FOR CANCER SURVIVORS: SCNS-TARGET can help researchers and healthcare professionals determine unmet needs and inform requirements for new services and interventions, among patients using IBP therapies.
Description
Date
2025
Publisher
Collections
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Article
Citation
Crowe L, Brown MC, Lecouturier J, Greystoke A, Nuryunarsih D, Rimmer B, et al. Development of the SCNS-TARGET: a new tool to assess unmet needs in cancer patients utilising immuno-, biological or precision therapies. Journal of cancer survivorship : research and practice. 2025 Apr 10. PubMed PMID: 40208508. Epub 2025/04/10. eng.