Congenital anomalies and genetic syndromes in 173 cases of medulloblastoma.
AffiliationDepartment of Cancer Genetics, Paterson Institute for Cancer Research, Manchester, England.
MetadataShow full item record
AbstractOne hundred seventy-three consecutive cases of medulloblastoma recorded in the Manchester Children's Tumour Registry from 1954 to 1989 were studied. After review of case notes, X-rays, and health surveys the clinical outcome and incidence of congenital anomaly was determined. A previously unreported association with Rubinstein Taybi syndrome was found. Evidence of a genetic syndrome or congenital anomaly was found in 6.4%. These figures provide further evidence of the higher-than-expected incidence of congenital abnormalities.
CitationCongenital anomalies and genetic syndromes in 173 cases of medulloblastoma. 1993, 21 (6):433-4 Med. Pediatr. Oncol.
JournalMedical and Pediatric Oncology
- The incidence of Gorlin syndrome in 173 consecutive cases of medulloblastoma.
- Authors: Evans DG, Farndon PA, Burnell LD, Gattamaneni HR, Birch JM
- Issue date: 1991 Nov
- Childhood medulloblastoma in northwest England 1954 to 1997: incidence and survival.
- Authors: Alston RD, Newton R, Kelsey A, Newbould MJ, Birch JM, Lawson B, McNally RJ
- Issue date: 2003 May
- A review of astrocytoma in childhood.
- Authors: Kibirige MS, Birch JM, Campbell RH, Gattamaneni HR, Blair V
- Issue date: 1989
- Congenital ichthyosis and medulloblastoma.
- Authors: Walach N
- Issue date: 1977
- Incidence and severity of postoperative cerebellar mutism syndrome in children with medulloblastoma: a prospective study by the Children's Oncology Group.
- Authors: Robertson PL, Muraszko KM, Holmes EJ, Sposto R, Packer RJ, Gajjar A, Dias MS, Allen JC, Children's Oncology Group.
- Issue date: 2006 Dec