Divergent differentiation in small round-cell tumours of the soft tissues with neural features--an analysis of 10 cases.
AffiliationDepartment of Histopathology, Christie Hospital, Manchester, UK.
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AbstractA series of 10 small round-cell tumours, having in common evidence of neural differentiation, were investigated by immunohistochemistry and electronmicroscopy. In seven, evidence of divergent muscle and/or epithelial differentiation was found. This phenomenon thus appears more common than previously appreciated and suggests that there may be a continuous and overlapping phenotypic spectrum from Ewing's tumour of soft tissue to intra-abdominal desmoplastic small cell tumour.
CitationDivergent differentiation in small round-cell tumours of the soft tissues with neural features--an analysis of 10 cases. 1993, 23 (1):1-9 Histopathology