The value of exfoliative cytology in the diagnosis of rectal malignancy.
Affiliation
Department of Surgery, Christie Hospital, Withington, Manchester, UK.Issue Date
1993-07
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This study has assessed the feasibility and reliability of cytology smears taken from patients with known rectal carcinomas without the use of any special instruments. In a pilot study of 23 patients who all had proved rectal cancer, 19 patients had satisfactory smears, one of which produced a false negative result. The remaining 18 displayed varying degrees of dysplasia (10) or frank malignancy (8). One of the patients with a smear containing severely dysplastic cells had a negative biopsy but had clear clinical and radiological evidence of a rectal tumour. Subsequently, a blind controlled study was undertaken on 29 patients with either carcinoma, proctitis or a normal rectum. All 29 sets of smears were of diagnostic quality and were correctly diagnosed as benign or malignant by the cytologist who had no knowledge of the clinical diagnosis. This is a rapid and simple diagnostic test which, if positive for malignancy, allows treatment to be planned at the first consultation. In combination with a forceps biopsy, the rate of positive diagnosis may be increased. A dysplastic smear adds to the level of clinical suspicion and confirms the need for biopsy of a lesion.Citation
The value of exfoliative cytology in the diagnosis of rectal malignancy. 1993, 8 (2):78-80 Int J Colorectal DisJournal
International Journal of Colorectal DiseaseDOI
10.1007/BF00299332PubMed ID
8409691Type
ArticleLanguage
enISSN
0179-1958ae974a485f413a2113503eed53cd6c53
10.1007/BF00299332
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