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    Definition of local recurrence after surgery for rectal carcinoma.

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    Authors
    Marsh, P J
    James, Roger D
    Schofield, Philip F
    Affiliation
    Department of Surgery, Christie Hospital NHS Trust, Withington, Manchester, UK.
    Issue Date
    1995-04
    
    Metadata
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    Abstract
    Local recurrence rates of rectal carcinoma have been analysed among 284 patients in a prospective randomized multicentre trial of adjuvant preoperative radiotherapy for locally advanced rectal carcinoma. Wide variations in local recurrence rates are demonstrated depending on the definition of local recurrence employed and the subgroup studied. Thus after surgical operation alone, rates as high as 43.3 per cent or as low as 12.7 per cent can be calculated. After both adjuvant preoperative radiotherapy and operation the overall local recurrence rate is 12.8 per cent, although the local recurrence rate inside the radiotherapy field (true recurrence) may be as low as 2.3 per cent. It is recommended that local recurrence after operation for rectal carcinoma be defined as any detectable local disease at follow-up, occurring either alone or in conjunction with generalized recurrence, in patients who have undergone resection. A rate should be given both for all patients and for those operated on for cure, but not for the latter group alone as this could introduce bias.
    Citation
    Definition of local recurrence after surgery for rectal carcinoma. 1995, 82 (4):465-8 Br J Surg
    Journal
    The British Journal of Surgery
    URI
    http://hdl.handle.net/10541/98148
    DOI
    10.1002/bjs.1800820412
    PubMed ID
    7542142
    Type
    Article
    Language
    en
    ISSN
    0007-1323
    ae974a485f413a2113503eed53cd6c53
    10.1002/bjs.1800820412
    Scopus Count
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    All Christie Publications

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