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    The Value of Anatomic Staging and Other Prognostic Factors in Small Cell Lung Cancer Management: A View of European Studies.

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    Authors
    Thatcher, Nick
    Anderson, Heather
    Burt, Paul A
    Stout, Ronald
    Affiliation
    Cancer Research Campaign Department of Medical Oncology, Christie Hospital & Holt Radium Institute, Manchester, England
    Issue Date
    1995-01
    
    Metadata
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    Abstract
    The need to include simple laboratory indices and performance status evaluation in treatment decision making has been shown by multivariate analyses. The conventional limited-stage extensive-stage division of prognostic groups no longer provides sufficient information. Indeed, some patients in the limited-stage group have a poor prognosis and about one quarter of patients in the extensive-stage group have a better prognosis when information from performance status and pretreatment biochemistry is taken into account. There is no rational clinical need for elaborate staging procedures, eg, computed tomography scanning or bone marrow examination, in the majority of patients with small cell lung cancer. Adequate information for defining prognostic groups can be obtained by using performance status, lactate dehydrogenase, and other biochemical tests such as sodium, alkaline phosphatase, and albumin. Thereby the cost to the patient of unnecessary burdensome investigations and to health care could both be reduced.
    Citation
    The Value of Anatomic Staging and Other Prognostic Factors in Small Cell Lung Cancer Management: A View of European Studies. 1995, 5 (1):19-26 Semin Radiat Oncol
    Journal
    Seminars in Radiation Oncology
    URI
    http://hdl.handle.net/10541/98096
    DOI
    10.1016/S1053-4296(05)80005-0
    PubMed ID
    10717121
    Type
    Article
    ISSN
    1532-9461
    ae974a485f413a2113503eed53cd6c53
    10.1016/S1053-4296(05)80005-0
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