Affiliation
Cancer Research Campaign Department of Cancer Genetics, Paterson Institute for Cancer Research, Christie Hospital NHS Trust, Manchester.Issue Date
1995-06
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Show full item recordAbstract
The gene loci CDK4, GLI, CHOP and MDM2 have been mapped to the q13-q15 region of chromosome 12. Using fluorescence in situ hybridization onto simultaneously DAPI-banded metaphase chromosomes and interphase nuclei, we have more precisely mapped and ordered these loci, together with a number of Genethon microsatellite markers. GLI and CHOP localize to 12q13.3-14.1, CDK4 to 12q14 and MDM2 to 12q14.3-q15, and the gene order is cen-GLI/CHOP-CDK4-MDM2. The Genethon microsatellites D12S80 and D12S83 flank MDM2.Citation
Mapping of gene loci in the Q13-Q15 region of chromosome 12. 1995, 3 (4):261-2 Chromosome Res.Journal
Chromosome ResearchDOI
10.1007/BF00713052PubMed ID
7606365Type
ArticleLanguage
enISSN
0967-3849ae974a485f413a2113503eed53cd6c53
10.1007/BF00713052
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