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dc.contributor.authorMenagé, H D
dc.contributor.authorHarrison, G I
dc.contributor.authorPotten, Christopher S
dc.contributor.authorYoung, A R
dc.contributor.authorHawk, J L
dc.date.accessioned2010-04-30T15:49:59Z
dc.date.available2010-04-30T15:49:59Z
dc.date.issued1995-12
dc.identifier.citationThe action spectrum for induction of chronic actinic dermatitis is similar to that for sunburn inflammation. 1995, 62 (6):976-9 Photochem. Photobiol.en
dc.identifier.issn0031-8655
dc.identifier.pmid8570744
dc.identifier.urihttp://hdl.handle.net/10541/97771
dc.description.abstractThe action spectrum for induction of the abnormal cutaneous response at 24 h in the photosensitivity disorder chronic actinic dermatitis (CAD) was determined in 15 patients and found to be the same in shape as that for normal sunburn in fair-skinned individuals at 24 h, as determined for 47 control volunteers, although displaced in magnitude. This suggests that an endogenous chromophore(s), the same as or similar to that/those responsible for human sunburn, may be responsible for initiation of the abnormal reaction to irradiation in CAD, and that the putative antigen associated with the CAD reaction may be derived from that/those or associated molecules.
dc.language.isoenen
dc.subject.meshAged
dc.subject.meshAged, 80 and over
dc.subject.meshChronic Disease
dc.subject.meshErythema
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshMiddle Aged
dc.subject.meshPhotosensitivity Disorders
dc.subject.meshReference Values
dc.subject.meshSpectrophotometry, Ultraviolet
dc.subject.meshSunburn
dc.subject.meshUltraviolet Rays
dc.titleThe action spectrum for induction of chronic actinic dermatitis is similar to that for sunburn inflammation.en
dc.typeArticleen
dc.contributor.departmentDepartment of Photobiology, St. John's Institute of Dermatology, United Medical School of Guy's Hospital, London.en
dc.identifier.journalPhotochemistry and Photobiologyen
html.description.abstractThe action spectrum for induction of the abnormal cutaneous response at 24 h in the photosensitivity disorder chronic actinic dermatitis (CAD) was determined in 15 patients and found to be the same in shape as that for normal sunburn in fair-skinned individuals at 24 h, as determined for 47 control volunteers, although displaced in magnitude. This suggests that an endogenous chromophore(s), the same as or similar to that/those responsible for human sunburn, may be responsible for initiation of the abnormal reaction to irradiation in CAD, and that the putative antigen associated with the CAD reaction may be derived from that/those or associated molecules.


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