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    The action spectrum for induction of chronic actinic dermatitis is similar to that for sunburn inflammation.

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    Authors
    Menagé, H D
    Harrison, G I
    Potten, Christopher S
    Young, A R
    Hawk, J L
    Affiliation
    Department of Photobiology, St. John's Institute of Dermatology, United Medical School of Guy's Hospital, London.
    Issue Date
    1995-12
    
    Metadata
    Show full item record
    Abstract
    The action spectrum for induction of the abnormal cutaneous response at 24 h in the photosensitivity disorder chronic actinic dermatitis (CAD) was determined in 15 patients and found to be the same in shape as that for normal sunburn in fair-skinned individuals at 24 h, as determined for 47 control volunteers, although displaced in magnitude. This suggests that an endogenous chromophore(s), the same as or similar to that/those responsible for human sunburn, may be responsible for initiation of the abnormal reaction to irradiation in CAD, and that the putative antigen associated with the CAD reaction may be derived from that/those or associated molecules.
    Citation
    The action spectrum for induction of chronic actinic dermatitis is similar to that for sunburn inflammation. 1995, 62 (6):976-9 Photochem. Photobiol.
    Journal
    Photochemistry and Photobiology
    URI
    http://hdl.handle.net/10541/97771
    PubMed ID
    8570744
    Type
    Article
    Language
    en
    ISSN
    0031-8655
    Collections
    All Paterson Institute for Cancer Research

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