Show simple item record

dc.contributor.authorNadali, Gianpaolo
dc.contributor.authorDe Wynter, Erika A
dc.contributor.authorTesta, Nydia G
dc.date.accessioned2010-04-26T13:57:27Z
dc.date.available2010-04-26T13:57:27Z
dc.date.issued1995
dc.identifier.citationCD34 cell separation: from basic research to clinical applications. 1995, 25 (3):121-7 Int. J. Clin. Lab. Res.en
dc.identifier.issn0940-5437
dc.identifier.pmid8562973
dc.identifier.urihttp://hdl.handle.net/10541/97399
dc.description.abstractAdvances in the immunological identification of primitive haematopoietic cells have led to the development of various techniques for their characterisation and purification. The expression of the CD34 antigen by the stem cell compartment has been exploited for these purposes. Separation systems capable of isolating CD34+ cells on a large scale are finding use in the clinic. Areas of interest overlap for both researchers and clinicians, and efforts to mobilise, characterise, purify and transplant these cells continue. Different CD34 purification systems are reviewed, focusing on their possible applications in different research fields. Clinical results of CD34+ selection and the possible future applications of this technology in the clinic are also reported.
dc.language.isoenen
dc.subject.meshAntigens, CD34
dc.subject.meshCell Separation
dc.subject.meshHumans
dc.subject.meshStem Cell Transplantation
dc.subject.meshStem Cells
dc.titleCD34 cell separation: from basic research to clinical applications.en
dc.typeArticleen
dc.contributor.departmentCRC Department of Experimental Haematology, Paterson Institute for Cancer Research, Manchester, UK.en
dc.identifier.journalInternational Journal of Clinical & Laboratory Researchen
html.description.abstractAdvances in the immunological identification of primitive haematopoietic cells have led to the development of various techniques for their characterisation and purification. The expression of the CD34 antigen by the stem cell compartment has been exploited for these purposes. Separation systems capable of isolating CD34+ cells on a large scale are finding use in the clinic. Areas of interest overlap for both researchers and clinicians, and efforts to mobilise, characterise, purify and transplant these cells continue. Different CD34 purification systems are reviewed, focusing on their possible applications in different research fields. Clinical results of CD34+ selection and the possible future applications of this technology in the clinic are also reported.


This item appears in the following Collection(s)

Show simple item record