Show simple item record

dc.contributor.authorKałuza, Jen
dc.contributor.authorKrupiński, Jen
dc.contributor.authorKumar, Patriciaen
dc.contributor.authorKumar, Shanten
dc.contributor.authorWang, Ji Minen
dc.date.accessioned2010-04-23T11:06:28Z
dc.date.available2010-04-23T11:06:28Z
dc.date.issued1994
dc.identifier.citationVCAM-1 expression on reactive and tumour astrocytes. 1994, 32 (1):17-20 Folia Histochem. Cytobiol.en
dc.identifier.issn0239-8508
dc.identifier.pmid7517897
dc.identifier.urihttp://hdl.handle.net/10541/97287
dc.description.abstractIn our studies we used a monoclonal antibody recognizing the vascular adhesion molecule (VCAM-1). Tissue samples were collected at autopsy from human brain infarcts and from brain tumours, removed during surgical procedure (Neurological and Neurosurgical Clinic, Cracow). A novel, unexpected finding were VCAM-1-positive fibrous astrocytes in the stroke tissue, and astrocyte-like cells in the tumours. No staining was obtained either in the contralateral hemisphere or outside of ischemic areas. Likewise, no positive staining of cells was seen outside the tumour tissue. The above findings, taken together, strongly support the concept that astrocytes take part in the immune defense during various pathological processes in the human brain.
dc.language.isoenen
dc.subjectBrain Canceren
dc.subject.meshAstrocytes
dc.subject.meshAstrocytoma
dc.subject.meshBrain Neoplasms
dc.subject.meshCell Adhesion Molecules
dc.subject.meshGlioblastoma
dc.subject.meshHumans
dc.subject.meshImmunohistochemistry
dc.subject.meshVascular Cell Adhesion Molecule-1
dc.titleVCAM-1 expression on reactive and tumour astrocytes.en
dc.typeArticleen
dc.contributor.departmentDepartment of Neuropathology, Collegium Medicum, Jagiellonian University, Cracow, Poland.en
dc.identifier.journalFolia Histochemica et Cytobiologicaen
html.description.abstractIn our studies we used a monoclonal antibody recognizing the vascular adhesion molecule (VCAM-1). Tissue samples were collected at autopsy from human brain infarcts and from brain tumours, removed during surgical procedure (Neurological and Neurosurgical Clinic, Cracow). A novel, unexpected finding were VCAM-1-positive fibrous astrocytes in the stroke tissue, and astrocyte-like cells in the tumours. No staining was obtained either in the contralateral hemisphere or outside of ischemic areas. Likewise, no positive staining of cells was seen outside the tumour tissue. The above findings, taken together, strongly support the concept that astrocytes take part in the immune defense during various pathological processes in the human brain.


This item appears in the following Collection(s)

Show simple item record