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    Male fertility after VAPEC-B chemotherapy for Hodgkin's disease and non-Hodgkin's lymphoma.

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    Authors
    Radford, John A
    Clark, S
    Crowther, Derek
    Shalet, Stephen M
    Affiliation
    CRC Department of Medical Oncology, Christie Hospital, Manchester, UK.
    Issue Date
    1994-02
    
    Metadata
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    Abstract
    Semen analysis was performed in 14 men a median of 13.5 months after completion of VAPEC-B chemotherapy for Hodgkin's disease or non-Hodgkin's lymphoma. Semen from 12 patients contained motile spermatozoa, and in nine cases the count was > 20 million ml-1. One patient was azoospermic (VAPEC-B followed by pelvic radiotherapy) and another had a count of 21 million ml-1 but sperm were non-motile. These findings suggest that, in the majority of cases, VAPEC-B chemotherapy does not cause permanent damage to the male germinal epithelium. A more detailed study of gonadal function in males and females before and after treatment with VAPEC-B for Hodgkin's disease is currently in progress.
    Citation
    Male fertility after VAPEC-B chemotherapy for Hodgkin's disease and non-Hodgkin's lymphoma. 1994, 69 (2):379-81 Br. J. Cancer
    Journal
    British Journal of Cancer
    URI
    http://hdl.handle.net/10541/97142
    PubMed ID
    7507693
    Type
    Article
    Language
    en
    ISSN
    0007-0920
    Collections
    All Christie Publications

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