Show simple item record

dc.contributor.authorWatanabe, H
dc.contributor.authorHendry, Jolyon H
dc.date.accessioned2010-04-20T15:25:13Z
dc.date.available2010-04-20T15:25:13Z
dc.date.issued1994-06
dc.identifier.citationChanges in normal and abnormal colony formation of thyroid cells in vivo, when transplanted at 1 day or 6 weeks after X-irradiation in situ. 1994, 35 (2):116-22 J. Radiat. Res.en
dc.identifier.issn0449-3060
dc.identifier.pmid7965990
dc.identifier.doi10.1269/jrr.35.116
dc.identifier.urihttp://hdl.handle.net/10541/96939
dc.description.abstractThyroid cells were given 5.5 Gy X-rays in situ and transplanted after 1 day or after 6 weeks to form colonies in fat pads. The colony-forming efficiency unexpectedly decreased by a factor of about 2 with this increase in delay time before transplantation. In addition, there was a concomitant marked increase above the control levels in the proportion of new structures of thyroid origin containing abnormal follicles. These quantitative and qualitative increases in injury may be related to the gradual expression of thyroid abnormalities following irradiation in situ, and they may have implications for the recovery of functional tissue subunits in other organs.
dc.language.isoenen
dc.subject.meshAnimals
dc.subject.meshCell Division
dc.subject.meshCell Transplantation
dc.subject.meshMale
dc.subject.meshRadiation Tolerance
dc.subject.meshRats
dc.subject.meshRats, Inbred F344
dc.subject.meshThyroid Gland
dc.titleChanges in normal and abnormal colony formation of thyroid cells in vivo, when transplanted at 1 day or 6 weeks after X-irradiation in situ.en
dc.typeArticleen
dc.contributor.departmentDepartment of Cancer Research, Hiroshima University, Japan.en
dc.identifier.journalJournal of Radiation Researchen
html.description.abstractThyroid cells were given 5.5 Gy X-rays in situ and transplanted after 1 day or after 6 weeks to form colonies in fat pads. The colony-forming efficiency unexpectedly decreased by a factor of about 2 with this increase in delay time before transplantation. In addition, there was a concomitant marked increase above the control levels in the proportion of new structures of thyroid origin containing abnormal follicles. These quantitative and qualitative increases in injury may be related to the gradual expression of thyroid abnormalities following irradiation in situ, and they may have implications for the recovery of functional tissue subunits in other organs.


This item appears in the following Collection(s)

Show simple item record