Haemopoietic growth factor and dose intensity in high-grade and intermediate-grade lymphoma.
| dc.contributor.author | Pettengell, Ruth | |
| dc.contributor.author | Crowther, Derek | |
| dc.date.accessioned | 2010-04-08T16:24:51Z | |
| dc.date.available | 2010-04-08T16:24:51Z | |
| dc.date.issued | 1994 | |
| dc.identifier.citation | Haemopoietic growth factor and dose intensity in high-grade and intermediate-grade lymphoma. 1994, 5 Suppl 2:133-41 Ann. Oncol. | en |
| dc.identifier.issn | 0923-7534 | |
| dc.identifier.pmid | 7911317 | |
| dc.identifier.uri | http://hdl.handle.net/10541/96051 | |
| dc.description.abstract | Here we review the evidence that cytotoxic dose intensity is an important determinant of outcome in high- and intermediate-grade non-Hodgkin's lymphoma. The results of retrospective analyses and prospective studies support this proposition but confirmatory studies are required. We discuss the role of haemopoietic growth factors and mobilized peripheral blood progenitor cells to increase dose intensity. Studies using these modalities will enable the importance of dose intensity to be tested. | |
| dc.language.iso | en | en |
| dc.subject | Haematopoietic Cell Growth Factors | en |
| dc.subject | Haematopoietic Stem Cell Transplantation | en |
| dc.subject.mesh | Antineoplastic Combined Chemotherapy Protocols | |
| dc.subject.mesh | Blood Component Transfusion | |
| dc.subject.mesh | Blood Transfusion, Autologous | |
| dc.subject.mesh | Bone Marrow Diseases | |
| dc.subject.mesh | Clinical Trials as Topic | |
| dc.subject.mesh | Combined Modality Therapy | |
| dc.subject.mesh | Hematopoietic Cell Growth Factors | |
| dc.subject.mesh | Hematopoietic Stem Cell Transplantation | |
| dc.subject.mesh | Humans | |
| dc.subject.mesh | Immunologic Factors | |
| dc.subject.mesh | Lymphoma, Non-Hodgkin | |
| dc.subject.mesh | Multicenter Studies as Topic | |
| dc.subject.mesh | Multivariate Analysis | |
| dc.subject.mesh | Prognosis | |
| dc.subject.mesh | Prospective Studies | |
| dc.subject.mesh | Randomized Controlled Trials as Topic | |
| dc.subject.mesh | Recombinant Proteins | |
| dc.subject.mesh | Remission Induction | |
| dc.subject.mesh | Retrospective Studies | |
| dc.subject.mesh | Salvage Therapy | |
| dc.subject.mesh | Survival Analysis | |
| dc.subject.mesh | Treatment Outcome | |
| dc.title | Haemopoietic growth factor and dose intensity in high-grade and intermediate-grade lymphoma. | en |
| dc.type | Article | en |
| dc.contributor.department | CRC Department of Medical Oncology, Christie Hospital NHS Trust, Manchester, United Kingdom. | en |
| dc.identifier.journal | Annals of Oncology | en |
| html.description.abstract | Here we review the evidence that cytotoxic dose intensity is an important determinant of outcome in high- and intermediate-grade non-Hodgkin's lymphoma. The results of retrospective analyses and prospective studies support this proposition but confirmatory studies are required. We discuss the role of haemopoietic growth factors and mobilized peripheral blood progenitor cells to increase dose intensity. Studies using these modalities will enable the importance of dose intensity to be tested. |