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dc.contributor.authorBanerjee, Saumitra S
dc.contributor.authorBishop, P W
dc.contributor.authorNicholson, C M
dc.contributor.authorEyden, Brian P
dc.date.accessioned2010-04-08T11:51:43Z
dc.date.available2010-04-08T11:51:43Z
dc.date.issued1996-11
dc.identifier.citationMalignant melanoma showing smooth muscle differentiation. 1996, 49 (11):950-1 J. Clin. Pathol.en
dc.identifier.issn0021-9746
dc.identifier.pmid8944620
dc.identifier.doi10.1136/jcp.49.11.950
dc.identifier.urihttp://hdl.handle.net/10541/95966
dc.description.abstractA unique case of a metastatic non-desmoplastic sarcomatoid malignant melanoma in an axillary lymph node showing smooth muscle differentiation in a 54 year old woman is described. The tumour cells exhibited alpha-smooth muscle actin, HHF-35 and desmin positivity but were negative for S100 protein and HMB-45. Ultrastructural examination revealed smooth muscle phenotype and there was no evidence of myofibroblastic differentiation, a feature described previously in desmoplastic melanomas.
dc.language.isoenen
dc.subject.meshActins
dc.subject.meshDesmin
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshImmunohistochemistry
dc.subject.meshLymphatic Metastasis
dc.subject.meshMelanoma
dc.subject.meshMiddle Aged
dc.titleMalignant melanoma showing smooth muscle differentiation.en
dc.typeArticleen
dc.contributor.departmentDepartment of Pathology, Christie Hospital, Manchester.en
dc.identifier.journalJournal of Clinical Pathologyen
html.description.abstractA unique case of a metastatic non-desmoplastic sarcomatoid malignant melanoma in an axillary lymph node showing smooth muscle differentiation in a 54 year old woman is described. The tumour cells exhibited alpha-smooth muscle actin, HHF-35 and desmin positivity but were negative for S100 protein and HMB-45. Ultrastructural examination revealed smooth muscle phenotype and there was no evidence of myofibroblastic differentiation, a feature described previously in desmoplastic melanomas.


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