Long-term control of polycythemia rubra vera with recombinant alpha interferon.
Affiliation
Department of Haematology, Hammersmith Hospital, London, UK.Issue Date
1996-03
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The natural history of PRV is characterized by a prolonged period of myeloproliferation chiefly affecting the red cell series. It can be controlled by venesection and cytotoxic agents. In this case report the patient declined further 'standard' chemotherapy to control his disease and the use of relatively low doses of IFN-a was successful in our patient in controlling myeloproliferation and stabilizing the disease over a prolonged period. These results support the use of IFN-a, not only as a means of myelosuppression in PRV but also as an agent with the potential to prevent disease progression.Citation
Long-term control of polycythemia rubra vera with recombinant alpha interferon. 1996, 14 (1):37-40 Hematol OncolJournal
Hematological oncologyDOI
10.1002/(SICI)1099-1069(199603)14:1<37::AID-HON564>3.0.CO;2-FPubMed ID
8613135Type
ArticleLanguage
enISSN
0278-0232ae974a485f413a2113503eed53cd6c53
10.1002/(SICI)1099-1069(199603)14:1<37::AID-HON564>3.0.CO;2-F
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