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    Primary small cell neuroendocrine carcinoma of the kidney.

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    Authors
    Morgan, K G
    Banerjee, Saumitra S
    Eyden, Brian P
    Barnard, R J
    Affiliation
    Department of Pathology, Christie Hospital NHS Trust, Manchester, United Kingdom.
    Issue Date
    2010-04-07T15:30:09Z
    
    Metadata
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    Abstract
    The histological, immunohistochemical, and ultrastructural features of a primary small cell neuroendocrine carcinoma of the renal parenchyma are described. Tumor cells were positive for cytokeratin, neuron-specific enolase, and Leu 7, but Grimelius- and chromogranin-negative. They also exhibited positivity with anti-MIC2 antibody. By electron microscopy, tonofibrils, primitive desmosomes, and dense-core granules with a neuroendocrine appearance were present. This is only the 7th recorded example of such a tumor at this site, which showed an aggressive course characterized by widespread bony metastases.
    Citation
    Primary small cell neuroendocrine carcinoma of the kidney., 20 (2):141-4 Ultrastruct Pathol
    Journal
    Ultrastructural Pathology
    URI
    http://hdl.handle.net/10541/95920
    DOI
    10.3109/01913129609016308
    PubMed ID
    8882359
    Type
    Article
    Language
    en
    ISSN
    0191-3123
    ae974a485f413a2113503eed53cd6c53
    10.3109/01913129609016308
    Scopus Count
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