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    Implications for immunosurveillance of altered HLA class I phenotypes in human tumours.

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    Authors
    Garrido, F
    Ruiz-Cabello, F
    Cabrera, T
    Pérez-Villar, J J
    López-Botet, M
    Duggan-Keen, M
    Stern, Peter L
    Affiliation
    Dpto de Análisis Clinicos e Inmunología, Hospital Universitario Virgen de las Nieves, Universidad de Granada, Spain. Fgarrido@golialt. ugr.es
    Issue Date
    1997-02
    
    Metadata
    Show full item record
    Abstract
    HLA class I downregulation is a frequent event associated with tumour invasion and development. Altered HLA class I tumour phenotypes can have profound effects on T-cell and natural killer (NK)-cell antitumour responses. Here, Federico Garrido and colleagues analyse these altered tumour phenotypes in detail, indicating their potential relevance for implementation of immunotherapeutic protocols and strategies to overcome tumour escape mechanisms.
    Citation
    Implications for immunosurveillance of altered HLA class I phenotypes in human tumours. 1997, 18 (2):89-95 Immunol. Today
    Journal
    Immunology today
    URI
    http://hdl.handle.net/10541/95476
    DOI
    10.1016/S0167-5699(96)10075-X
    PubMed ID
    9057360
    Type
    Article
    Language
    en
    ISSN
    0167-5699
    ae974a485f413a2113503eed53cd6c53
    10.1016/S0167-5699(96)10075-X
    Scopus Count
    Collections
    All Paterson Institute for Cancer Research

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