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    Mapping of 22 new ESTs around a tumor suppressor gene and a senescence gene at 6q16-->q21.

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    Authors
    Morelli, C
    Cardona, F
    Boyle, John M
    Negrini, M
    Barbanti-Brodano, G
    Affiliation
    Department of Experimental and Diagnostic Medicine, University of Ferrara, Italy.
    Issue Date
    1997
    
    Metadata
    Show full item record
    Abstract
    Twenty two expressed sequence tags (ESTs) have been mapped at the border of 6q16-->q21 and at the proximal end of 6q21, a candidate for two tumor suppressor genes and a senescence gene. Use of a translocation and deletion hybrid panel together with a 4-Mb YAC contig allowed us to precisely define the position of the ESTs. Thirteen ESTs were placed within the 4-Mb interval at the proximal portion of 6q21 using a restriction map of the YAC contig, seven ESTs span a 2-Mb region on the 6q16-->q21 border, and two are distal to the contig. Refinement of the localization of these ESTs will provide substantial assistance in identifying new genes within the region 6q16-->q21.
    Citation
    Mapping of 22 new ESTs around a tumor suppressor gene and a senescence gene at 6q16-->q21. 1997, 79 (1-2):97-100 Cytogenet. Cell Genet.
    Journal
    Cytogenetics and Cell Genetics
    URI
    http://hdl.handle.net/10541/95463
    DOI
    10.1159/000134691
    PubMed ID
    9533021
    Type
    Article
    Language
    en
    ISSN
    0301-0171
    ae974a485f413a2113503eed53cd6c53
    10.1159/000134691
    Scopus Count
    Collections
    All Paterson Institute for Cancer Research

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