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    VS38 immunostaining in neuroendocrine tumours.

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    Authors
    Banerjee, Saumitra S
    Shanks, Jonathan H
    Hasleton, Philip S
    Affiliation
    Department of Histopathology, Christie Hospital NHS Trust, Manchester, UK.
    Issue Date
    1997-03
    
    Metadata
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    Abstract
    VS38 was originally described as a marker of neoplastic and non-neoplastic plasma cells. We recently described its immunoreactivity with melanocytic lesion. The aim of the present study was to investigate the reactivity of VS38 with various neuroendocrine tumours. Using paraffin sections of routinely processed archival tissue we found that 72% of 50 neuroendocrine tumours tested showed immunohistochemical positivity for VS38. A wide spectrum of neuroendocrine tumours were positive. Use of a panel of markers and awareness of the lack of specificity of VS38 will avoid misdiagnosis, particularly when neuroendocrine tumours and other lesions which react immunohistochemically with this antibody are located at unusual sites and exhibit plasmacytoid features.
    Citation
    VS38 immunostaining in neuroendocrine tumours. 1997, 30 (3):256-9 Histopathology
    Journal
    Histopathology
    URI
    http://hdl.handle.net/10541/94847
    DOI
    10.1046/j.1365-2559.1997.d01-599.x
    PubMed ID
    9088955
    Type
    Article
    Language
    en
    ISSN
    0309-0167
    ae974a485f413a2113503eed53cd6c53
    10.1046/j.1365-2559.1997.d01-599.x
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