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Angiotropic lymphoma with endocrine involvement.

dc.contributor.authorShanks, Jonathan H
dc.contributor.authorHarris, Maggie A
dc.contributor.authorHowat, A J
dc.contributor.authorFreemont, Anthony J
dc.date.accessioned2010-03-23T16:42:32Z
dc.date.available2010-03-23T16:42:32Z
dc.date.issued1997-08
dc.identifier.citationAngiotropic lymphoma with endocrine involvement. 1997, 31 (2):161-6 Histopathologyen
dc.identifier.issn0309-0167
dc.identifier.pmid9279568
dc.identifier.doi10.1046/j.1365-2559.1997.2260835.x
dc.identifier.urihttp://hdl.handle.net/10541/94748
dc.description.abstractAIMS: Two cases of angiotropic high-grade B-cell lymphoma are described in which involvement of endocrine glands was a prominent feature. METHODS AND RESULTS: One patient had marked unilateral adrenomegally due to lymphoma within adrenal blood vessels. He is alive 5 years after presentation following combination chemotherapy. The diagnosis was made at autopsy in the second patient who presented with pyrexia of unknown origin and had hypothyroidism and a thyroid nodule. The thyroid gland and pituitary showed striking involvement by angiotropic lymphoma and the thyroid nodule was a cavernous haemangioma heavily colonized by lymphoma cells. CONCLUSIONS: Our cases illustrate endocrine organ manifestations of this rare disease. The condition may respond to combination chemotherapy.
dc.language.isoenen
dc.subjectAdrenal Gland Canceren
dc.subjectThyroid Canceren
dc.subject.meshAdrenal Gland Neoplasms
dc.subject.meshAged
dc.subject.meshBlood Vessels
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshLymphoma
dc.subject.meshMale
dc.subject.meshMiddle Aged
dc.subject.meshThyroid Neoplasms
dc.titleAngiotropic lymphoma with endocrine involvement.en
dc.typeArticleen
dc.contributor.departmentDepartment of Histopathology, Christie Hospital, Manchester, UK.en
dc.identifier.journalHistopathologyen
html.description.abstractAIMS: Two cases of angiotropic high-grade B-cell lymphoma are described in which involvement of endocrine glands was a prominent feature. METHODS AND RESULTS: One patient had marked unilateral adrenomegally due to lymphoma within adrenal blood vessels. He is alive 5 years after presentation following combination chemotherapy. The diagnosis was made at autopsy in the second patient who presented with pyrexia of unknown origin and had hypothyroidism and a thyroid nodule. The thyroid gland and pituitary showed striking involvement by angiotropic lymphoma and the thyroid nodule was a cavernous haemangioma heavily colonized by lymphoma cells. CONCLUSIONS: Our cases illustrate endocrine organ manifestations of this rare disease. The condition may respond to combination chemotherapy.


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