Spindle cell carcinoma of the tongue in a long-term survivor of childhood acute lymphoblastic leukemia.
AffiliationDepartment of Paediatric Oncology, Royal Hospital for Sick Children, Edinburgh, Scotland.
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AbstractA 25-year-old male previously treated (age 9 years) for acute lymphoblastic leukemia developed a spindle cell carcinoma of the tongue. Possible causes for the development of his second malignancy are discussed. A combination of scatter from cranial irradiation, poor oral hygiene, alcohol consumption, and cigarette smoking is likely to be contributory. Genetic predisposition can never be fully excluded.
CitationSpindle cell carcinoma of the tongue in a long-term survivor of childhood acute lymphoblastic leukemia., 14 (1):79-83 Pediatr Hematol Oncol
JournalPediatric Hematology and Oncology