Relapse of intracranial germinoma 23 years postirradiation in a patient given growth hormone replacement.
AffiliationDepartment of Clinical Oncology, Christie Hospital NHS Trust, Manchester, United Kingdom.
MetadataShow full item record
AbstractThere is no clear evidence that growth hormone replacement therapy for treatment-related growth hormone deficiency in patients with childhood intracranial malignancies has a role in tumour relapse or second malignancy. A 16-year-old girl with an intracranial germinoma was treated with local radiotherapy and subsequently received growth hormone replacement therapy as an adult. Three years after starting growth hormone therapy, 23 years after her radiotherapy treatment, the patient's tumour recurred. Surveillance requirements for patients receiving growth hormone in this setting are discussed.
CitationRelapse of intracranial germinoma 23 years postirradiation in a patient given growth hormone replacement. 1997, 29 (1):41-4 Med. Pediatr. Oncol.
JournalMedical and Pediatric Oncology
- Tumour surveillance imaging in patients with extrapituitary tumours receiving growth hormone replacement.
- Authors: Chung TT, Drake WM, Evanson J, Walker D, Plowman PN, Chew SL, Grossman AB, Besser GM, Monson JP
- Issue date: 2005 Sep
- Growth hormone therapy and tumor recurrence. Findings in children with brain neoplasms and hypopituitarism.
- Authors: Arslanian SA, Becker DJ, Lee PA, Drash AL, Foley TP Jr
- Issue date: 1985 Apr
- Adult growth hormone replacement therapy and neuroimaging surveillance in brain tumour survivors.
- Authors: Jostel A, Mukherjee A, Hulse PA, Shalet SM
- Issue date: 2005 Jun
- Treatment of intracranial germinoma.
- Authors: Xu W, Zhang B, Chen T, Sun W
- Issue date: 1995 May
- Long-term results of radiotherapy for intracranial germinoma: a multi-institutional retrospective review of 126 patients.
- Authors: Ogawa K, Shikama N, Toita T, Nakamura K, Uno T, Onishi H, Itami J, Kakinohana Y, Kinjo T, Yoshii Y, Ito H, Murayama S
- Issue date: 2004 Mar 1