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    Tanning in human skin types II and III offers modest photoprotection against erythema.

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    Authors
    Sheehan, J M
    Potten, Christopher S
    Young, A R
    Affiliation
    Department of Photobiology, St John's Institute of Dermatology, St Thomas's Hospital, London, UK. j.sheehan@umds.ac.uk
    Issue Date
    1998-10
    
    Metadata
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    Abstract
    We have investigated the photoprotective properties of tanning using erythema as an endpoint. Previously unexposed buttock skin sites of 16 young, healthy adults (8 skin type II, and 8 skin type III) were exposed daily (Mon-Fri) for 2 weeks to 0.5 and 0.75 minimal erythema doses (MED) of solar-simulated radiation (SSR). Erythema and melanin levels were assessed daily both visually and quantitatively using a reflectance device. One week after the last tanning treatment, MED reassessments were made on pretreated sites and on adjacent nontreated sites, including sites from which stratum corneum was removed by tape stripping. Compared to skin type II, similar daily SSR treatments produced less erythema and more evident tanning in skin types III. Independent of skin type, all volunteers showed an increased MED value when assessed on the 0.75 MED- and 0.5 MED-treated sites compared to the MED value assessed on adjacent untreated sites. We express any increase in MED as an induced protection factor (IPF), i.e. (MED post-tan/MED pre-tan). Our data show mean IPF of 1.4 and of 2.1 in the 0.5 and 0.75 MED-treated sites respectively, in skin types II. Similar values were obtained in skin types III with IPF of 1.5 and 2.3 for the 0.5 and 0.75 MED-treated sites, respectively. In all cases, removal of the stratum corneum lowered the IPF by about 20%. Our results show that SSR-induced melanogenesis, whether in skin type II or III, offers only moderate protection against erythema and suggest that SSR-induced stratum corneum thickening affords less photoprotection than tanning.
    Citation
    Tanning in human skin types II and III offers modest photoprotection against erythema. 1998, 68 (4):588-92 Photochem. Photobiol.
    Journal
    Photochemistry and Photobiology
    URI
    http://hdl.handle.net/10541/92735
    PubMed ID
    9796443
    Type
    Article
    Language
    en
    ISSN
    0031-8655
    Collections
    All Paterson Institute for Cancer Research

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