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dc.contributor.authorWebster, Gareth J
dc.contributor.authorRowbottom, Carl G
dc.contributor.authorMackay, Ranald I
dc.date.accessioned2010-02-12T16:36:46Z
dc.date.available2010-02-12T16:36:46Z
dc.date.issued2009-12
dc.identifier.citationEvaluation of the impact of dental artefacts on intensity-modulated radiotherapy planning for the head and neck. 2009, 93 (3):553-8 Radiother Oncolen
dc.identifier.issn1879-0887
dc.identifier.pmid19897267
dc.identifier.doi10.1016/j.radonc.2009.10.006
dc.identifier.urihttp://hdl.handle.net/10541/92048
dc.description.abstractBACKGROUND AND PURPOSE: High density materials create severe artefacts in the computed tomography (CT) scans used for radiotherapy dose calculations. Increased use of intensity-modulated radiotherapy (IMRT) to treat oropharyngeal cancers raises concerns over the accuracy of the resulting dose calculation. This work quantifies their impact and evaluates a simple corrective technique. MATERIALS AND METHODS: Fifteen oropharyngeal patients with severe artefacts were retrospectively planned with IMRT using two different CT/density look-up tables. Each plan was recalculated using a corrected CT dataset to evaluate the dose distribution delivered to the patient. Plan quality in the absence of dental artefacts was similarly assessed. A range of dosimetric and radiobiological parameters were compared pre- and post-correction. RESULTS: Plans using a standard CT/density look-up table (density 1.8 g/cm(3)) revealed inconsistent inter-patient errors, mostly within clinical acceptance, although potentially significantly reducing target coverage for individual patients. Using an extended CT/density look-up table (density 10.0 g/cm(3)) greatly reduced the errors for 13/15 patients. In 2/15 patients with residual errors the CTV extended into the severely affected region and could be corrected by applying a simple manual correction. CONCLUSIONS: Use of an extended CT/density look-up table together with a simple manual bulk density correction reduces the impact of dental artefacts on head and neck IMRT planning to acceptable levels.
dc.language.isoenen
dc.subjectRadiotherapyen
dc.subjectHead and Neck Canceren
dc.subjectDose Calculationen
dc.titleEvaluation of the impact of dental artefacts on intensity-modulated radiotherapy planning for the head and neck.en
dc.typeArticleen
dc.contributor.departmentNorth Western Medical Physics, Christie Hospital NHS Foundation Trust, Manchester, UK. Gareth.Webster@physics.cr.man.ac.uken
dc.identifier.journalRadiotherapy and Oncologyen
html.description.abstractBACKGROUND AND PURPOSE: High density materials create severe artefacts in the computed tomography (CT) scans used for radiotherapy dose calculations. Increased use of intensity-modulated radiotherapy (IMRT) to treat oropharyngeal cancers raises concerns over the accuracy of the resulting dose calculation. This work quantifies their impact and evaluates a simple corrective technique. MATERIALS AND METHODS: Fifteen oropharyngeal patients with severe artefacts were retrospectively planned with IMRT using two different CT/density look-up tables. Each plan was recalculated using a corrected CT dataset to evaluate the dose distribution delivered to the patient. Plan quality in the absence of dental artefacts was similarly assessed. A range of dosimetric and radiobiological parameters were compared pre- and post-correction. RESULTS: Plans using a standard CT/density look-up table (density 1.8 g/cm(3)) revealed inconsistent inter-patient errors, mostly within clinical acceptance, although potentially significantly reducing target coverage for individual patients. Using an extended CT/density look-up table (density 10.0 g/cm(3)) greatly reduced the errors for 13/15 patients. In 2/15 patients with residual errors the CTV extended into the severely affected region and could be corrected by applying a simple manual correction. CONCLUSIONS: Use of an extended CT/density look-up table together with a simple manual bulk density correction reduces the impact of dental artefacts on head and neck IMRT planning to acceptable levels.


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