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    Screening by mammography, women with a family history of breast cancer.

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    Authors
    Lalloo, Fiona
    Boggis, C R
    Evans, D Gareth R
    Shenton, Andrew
    Threlfall, Anthony G
    Howell, Anthony
    Issue Date
    1998-05
    
    Metadata
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    Abstract
    The aim of this study was to describe the experience of screening women under the age of 50 years with a family history of breast cancer. 1259 women attended the Family History Clinic in Manchester for their first and subsequent consultations between 30 September 1992 and 30 April 1997. All women were under the age of 50 years at the initial consultation and had a lifetime risk of breast cancer of 1 in 6 or greater. Seven prevalent, seven incident and two interval cancers were detected. The number of invasive cancers expected to occur if this high risk population had not been screened was 8.45 (in 2722 person years at risk). 12 invasive cancers were detected, giving a ratio of 1.42 (95% confidence interval 0.73-2.48). The overall cancer detection rates in this young, at risk population were similar to those in older women in the National Health Service Breast Screening Programme. The number of cancers detected in the study was greater than expected in this population. As the numbers were small, a national trial needs to be undertaken to confirm these results and to determine the long term effects of screening.
    Citation
    Screening by mammography, women with a family history of breast cancer. 1998, 34 (6):937-40 Eur. J. Cancer
    Journal
    European Journal of Cancer
    URI
    http://hdl.handle.net/10541/92019
    PubMed ID
    9797712
    Type
    Article
    Language
    en
    ISSN
    0959-8049
    Collections
    All Christie Publications

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