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    Sources of error in bioimpedance spectroscopy.

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    Authors
    Bolton, M P
    Ward, L C
    Khan, A
    Campbell, I
    Nightingale, P
    Dewit, O
    Elia, M
    Affiliation
    Christie Hospital, Manchester, UK. bolton@fs1.with.man.ac.uk
    Issue Date
    1998-05
    
    Metadata
    Show full item record
    Abstract
    Two different makes of bioimpedance spectrometer (UniQuest-SEAC SFB-3 and Xitron 4000B) were used for a series of measurements on volunteers and patients in intensive care. Although each machine was accurate over the frequency range 5 to 500 kHz when bench tested on model resistor-capacitor circuits, significant differences in their recorded impedance parameters appeared when used in vivo, especially on intensive care patients. A series of laboratory tests was performed on each machine simulating the situation in vivo to identify possible reasons for these differences. Whilst stray capacitance in the environment was identified as the major contributor to variability in high-frequency performance, interaction between electrode impedance and lead positioning was also a factor. The observed phase shift with frequency or time delay (Td) used in the Xitron modeling software appears to be the result of a time constant caused by stray capacitance and so is unlikely to have any biological meaning. Significant differences in the in vivo numerical values produced by bioimpedance spectrometers may be attributed to instrument design, data processing and, in particular, the clinical environment.
    Citation
    Sources of error in bioimpedance spectroscopy. 1998, 19 (2):235-45 Physiol Meas
    Journal
    Physiological Measurement
    URI
    http://hdl.handle.net/10541/91970
    DOI
    10.1088/0967-3334/19/2/011
    PubMed ID
    9626688
    Type
    Article
    Language
    en
    ISSN
    0967-3334
    ae974a485f413a2113503eed53cd6c53
    10.1088/0967-3334/19/2/011
    Scopus Count
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