Exclusion of the genes CDKN2 and PTEN as causative gene defects in Li-Fraumeni syndrome.
Affiliation
CRC Section of Molecular Genetics, Paterson Institute for Cancer Research, Manchester, UK.Issue Date
1999-04
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We have analysed Li-Fraumeni syndrome families, previously shown to be negative for mutations in TP53, for mutations to the tumour suppressor genes PTEN and CDKN2. These genes function in cell cycle progression or are mutated in a variety of tumours. We have detected no mutations in the family members tested.Citation
Exclusion of the genes CDKN2 and PTEN as causative gene defects in Li-Fraumeni syndrome. 1999, 80 (1-2):9-10 Br. J. CancerJournal
British Journal of CancerDOI
10.1038/sj.bjc.6690313PubMed ID
10389970Type
ArticleLanguage
enISSN
0007-0920ae974a485f413a2113503eed53cd6c53
10.1038/sj.bjc.6690313
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