Immunohistochemical detection of steroid receptors in breast cancer: a working protocol.
Authors
Leake, RobinBarnes, Diana M
Pinder, Sarah
Ellis, Ian
Anderson, Elizabeth
Anderson, Tom
Adamson, Ruth
Rhodes, Anthony
Miller, Keith D
Walker, Rosemary
Affiliation
Department of Biochemistry and Molecular Biology, University of Glasgow, UK. R.Leake@bio.gla.ac.ukIssue Date
2000-08
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Show full item recordAbstract
The biochemical assay for the oestrogen receptor has shown the clinical value of knowing the concentration of the receptor within tissue. The immunohistochemical assay is rapidly taking over from the biochemical assay. Therefore, it is vital to have an equivalent scoring system that will have the same predictive value. This paper reports both a practical protocol and a scoring system that should achieve this aim. This approach should be applicable to many more biomarkers detected by immunohistochemistry.Citation
Immunohistochemical detection of steroid receptors in breast cancer: a working protocol. 2000, 53 (8):634-5 J. Clin. Pathol.Journal
Journal of Clinical PathologyDOI
10.1136/jcp.53.8.634PubMed ID
11002770Type
ArticleLanguage
enISSN
0021-9746ae974a485f413a2113503eed53cd6c53
10.1136/jcp.53.8.634
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