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dc.contributor.authorLaman, Heike
dc.contributor.authorMann, David J
dc.contributor.authorJones, Nic
dc.date.accessioned2009-12-29T11:14:00Z
dc.date.available2009-12-29T11:14:00Z
dc.date.issued2000-02
dc.identifier.citationViral-encoded cyclins. 2000, 10 (1):70-4 Curr. Opin. Genet. Dev.en
dc.identifier.issn0959-437X
dc.identifier.pmid10679390
dc.identifier.doi10.1016/S0959-437X(99)00045-3
dc.identifier.urihttp://hdl.handle.net/10541/88625
dc.description.abstractD-type cyclin homologs have been found in the genomes of herpesviruses associated with neoplasias. They appear to exploit features of G(1) cyclins but extend their properties to allow for deregulation of the cell cycle. Advances in the study of the molecular basis for these novel features as well as the potential role of viral cyclins in tumorigenesis are addressed.
dc.language.isoenen
dc.subjectCanceren
dc.subject.meshAnimals
dc.subject.meshCell Cycle
dc.subject.meshCyclin-Dependent Kinase Inhibitor p21
dc.subject.meshCyclin-Dependent Kinases
dc.subject.meshCyclins
dc.subject.meshHerpesviridae
dc.subject.meshHumans
dc.subject.meshNeoplasms
dc.subject.meshOncogenes
dc.subject.meshViral Proteins
dc.titleViral-encoded cyclins.en
dc.typeArticleen
dc.contributor.departmentMolecular Oncology Laboratory, Imperial Cancer Research Fund, London, WC2A 3PX, UK.en
dc.identifier.journalCurrent Opinion in Genetics & Developmenten
html.description.abstractD-type cyclin homologs have been found in the genomes of herpesviruses associated with neoplasias. They appear to exploit features of G(1) cyclins but extend their properties to allow for deregulation of the cell cycle. Advances in the study of the molecular basis for these novel features as well as the potential role of viral cyclins in tumorigenesis are addressed.


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