Epidemiology of herpesvirus papio infection in a large captive baboon colony: similarities to Epstein-Barr virus infection in humans.
AuthorsJenson, Hal B
Kennedy, Ronald C
Arrand, John R
AffiliationDepartments of Pediatrics and Microbiology, University of Texas Health Science Center at San Antonio, 78229-3900, USA. email@example.com
MetadataShow full item record
AbstractThe epidemiology of herpesvirus papio, a lymphocryptovirus similar to Epstein-Barr virus (EBV), was studied in a captive colony of >1900 baboons. Herpesvirus papio IgG antibody titers were measured by IFA. In total, 438 specimens from 296 baboons were assessed, including 116 serial specimens from 52 juveniles and 6 infants studied monthly for 1 year following birth and at age 18 months. Maternally derived antibody reached a nadir at 4 months of age. About 75% of animals at 12 months of age and >95% of animals after age 24 months demonstrated serologic evidence of herpesvirus papio infection. After age 3 years, the geometric mean titer was 1:60-75. The epidemiology of herpesvirus papio infection in baboons closely parallels that of EBV infection in humans. An animal model of lymphocryptovirus infection will facilitate investigations of human lymphocryptovirus biology.
CitationEpidemiology of herpesvirus papio infection in a large captive baboon colony: similarities to Epstein-Barr virus infection in humans. 2000, 181 (4):1462-6 J. Infect. Dis.
JournalThe Journal of Infectious Diseases
- Shedding and transmission of baboon Herpesvirus papio 2 (HVP2) in a breeding colony.
- Authors: Eberle R, Black DH, Lehenbauer TW, White GL
- Issue date: 1998 Feb
- Fatal lymphoproliferative disease associated with a novel gammaherpesvirus in a captive population of common marmosets.
- Authors: Ramer JC, Garber RL, Steele KE, Boyson JF, O'Rourke C, Thomson JA
- Issue date: 2000 Feb
- Prevalence of Herpesvirus papio 2 in baboons and identification of immunogenic viral polypeptides.
- Authors: Eberle R, Black DH, Blewett EL, White GL
- Issue date: 1997 Jun
- Naturally transmitted herpesvirus papio-2 infection in a black and white colobus monkey.
- Authors: Troan BV, Perelygina L, Patrusheva I, Wettere AJ, Hilliard JK, Loomis MR, Voe RS
- Issue date: 2007 Dec 15
- Survey of infections transmissible between baboons and humans, Cape Town, South Africa.
- Authors: Drewe JA, O'Riain MJ, Beamish E, Currie H, Parsons S
- Issue date: 2012 Feb