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    Small cell carcinoma of the uterine cervix: a clinicopathological review.

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    Authors
    Sykes, Andrew J
    Shanks, Jonathan H
    Davidson, Susan E
    Affiliation
    Department of Clinical Oncology, Christie Hospital NHS Trust, Manchester, M20 4BX, UK.
    Issue Date
    1999-02
    
    Metadata
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    Abstract
    Small cell carcinoma of the cervix is rare, with an aggressive natural history. We report on a series of 11 patients treated at the Christie Hospital, Manchester and examine their treatment and survival. Eleven patients with small cell carcinoma of the cervix were identified retrospectively from patient case notes. Treatment was individualised and included a variety of combinations of surgery radiotherapy and chemotherapy. Four patients were disease-free between 21 and 108 months (crude disease-free survival 36%). They presented with earlier disease and were older than the average for the group. They were all initially treated with radical radiotherapy. 7 patients died between 7 and 25 months. Despite combination chemotherapy, survival with advanced disease was poor. Published studies are small and fail to provide definitive answers on the best management of small cell carcinoma of the cervix. Drawing on the experience of small cell carcinoma of the lung however, combination therapy with radiotherapy, chemotherapy and possibly surgery requires careful assessment by an oncologist.
    Citation
    Small cell carcinoma of the uterine cervix: a clinicopathological review. 1999, 14 (2):381-6 Int. J. Oncol.
    Journal
    International Journal of Oncology
    URI
    http://hdl.handle.net/10541/87878
    PubMed ID
    9917517
    Type
    Article
    Language
    en
    ISSN
    1019-6439
    Collections
    All Christie Publications

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