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dc.contributor.authorEyden, Brian P
dc.date.accessioned2009-12-14T16:05:19Z
dc.date.available2009-12-14T16:05:19Z
dc.date.issued1999-08
dc.identifier.citationElectron microscopy in tumour diagnosis: continuing to complement other diagnostic techniques. 1999, 35 (2):102-8 Histopathologyen
dc.identifier.issn0309-0167
dc.identifier.pmid10460653
dc.identifier.doi10.1046/j.1365-2559.1999.0741b.x
dc.identifier.urihttp://hdl.handle.net/10541/87869
dc.description.abstractThe histopathological diagnosis of tumours has been transformed by immunohistochemistry. Used with experience and judgement, a panel of antibodies or antisera, combined when necessary with antigen retrieval, will enable the accurate typing of most problematic tumours. This has led many histopathologists to question whether the electron microscope has any residual utility for tumour diagnosis; the machines are large, costly to purchase and maintain, and will accept only minute samples of tissue. The following articles by Mierau and by Eyden, both strong advocates, comment on the current and future role of electron microscopy in tumour diagnosis.
dc.language.isoenen
dc.subjectCanceren
dc.subjectBiological Tumour Markersen
dc.subject.meshDiagnosis, Differential
dc.subject.meshHumans
dc.subject.meshImmunohistochemistry
dc.subject.meshMicroscopy, Electron
dc.subject.meshNeoplasms
dc.subject.meshOrganelles
dc.subject.meshReproducibility of Results
dc.subject.meshTumor Markers, Biological
dc.titleElectron microscopy in tumour diagnosis: continuing to complement other diagnostic techniques.en
dc.typeArticleen
dc.contributor.departmentDepartment of Histopathology, Christie Hospital NHS Trust, Manchester, UK.en
dc.identifier.journalHistopathologyen
html.description.abstractThe histopathological diagnosis of tumours has been transformed by immunohistochemistry. Used with experience and judgement, a panel of antibodies or antisera, combined when necessary with antigen retrieval, will enable the accurate typing of most problematic tumours. This has led many histopathologists to question whether the electron microscope has any residual utility for tumour diagnosis; the machines are large, costly to purchase and maintain, and will accept only minute samples of tissue. The following articles by Mierau and by Eyden, both strong advocates, comment on the current and future role of electron microscopy in tumour diagnosis.


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