Electron microscopy in tumour diagnosis: continuing to complement other diagnostic techniques.
AuthorsEyden, Brian P
AffiliationDepartment of Histopathology, Christie Hospital NHS Trust, Manchester, UK.
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AbstractThe histopathological diagnosis of tumours has been transformed by immunohistochemistry. Used with experience and judgement, a panel of antibodies or antisera, combined when necessary with antigen retrieval, will enable the accurate typing of most problematic tumours. This has led many histopathologists to question whether the electron microscope has any residual utility for tumour diagnosis; the machines are large, costly to purchase and maintain, and will accept only minute samples of tissue. The following articles by Mierau and by Eyden, both strong advocates, comment on the current and future role of electron microscopy in tumour diagnosis.
CitationElectron microscopy in tumour diagnosis: continuing to complement other diagnostic techniques. 1999, 35 (2):102-8 Histopathology
- Electron microscopy for tumour diagnosis: is it redundant?
- Authors: Mierau GW
- Issue date: 1999 Aug
- Electron microscopy in tumor diagnosis: indications for its use in the immunohistochemical era.
- Authors: Ordóñez NG, Mackay B
- Issue date: 1998 Dec
- Relative usefulness of electron microscopy and immunocytochemistry in tumour diagnosis: 10 years of retrospective analysis.
- Authors: Dar AU, Hird PM, Wagner BE, Underwood JC
- Issue date: 1992 Aug
- The comparative roles of electron microscopy and immunohistochemistry in the diagnosis of soft tissue tumours.
- Authors: Fisher C
- Issue date: 2006 Jan
- [Application of electron microscopy and immunohistochemistry to the study of malignant tumors: a review of their diagnostic importance].
- Authors: García-Tamayo J, Caleiras E, Blasco-Olaetxea E, Parada D, de García SE
- Issue date: 1997 Dec