• Login
    View Item 
    •   Home
    • The Christie Research Publications Repository
    • All Christie Publications
    • View Item
    •   Home
    • The Christie Research Publications Repository
    • All Christie Publications
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of ChristieCommunitiesTitleAuthorsIssue DateSubmit DateSubjectsThis CollectionTitleAuthorsIssue DateSubmit DateSubjects

    My Account

    LoginRegister

    Local Links

    The Christie WebsiteChristie Library and Knowledge Service

    Statistics

    Display statistics

    Assessment of bladder motion for clinical radiotherapy practice using cine-magnetic resonance imaging.

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Authors
    McBain, Catherine A
    Khoo, Vincent S
    Buckley, David L
    Sykes, Jonathan S
    Green, Melanie M
    Cowan, Richard A
    Hutchinson, Charles E
    Moore, Christopher J
    Price, Patricia M
    Affiliation
    Academic Department of Radiation Oncology, The University of Manchester, Christie Hospital NHS Foundation Trust, Wilmslow Road, Manchester, United Kingdom.
    Issue Date
    2009-11-01
    
    Metadata
    Show full item record
    Abstract
    PURPOSE: Organ motion is recognized as the principal source of inaccuracy in bladder radiotherapy (RT), but there is currently little information on intrafraction bladder motion. METHODS AND MATERIALS: We used cine-magnetic resonance imaging (cine-MRI) to study bladder motion relevant to intrafraction RT delivery. On two occasions, a 28 minute cine-MRI sequence was acquired from 10 bladder cancer patients and 5 control participants immediately after bladder emptying, after abstinence from drinking for the preceding hour. From the resulting cine sequences, bladder motion was subjectively assessed. To quantify bladder motion, the bladder was contoured in imaging volume sets at 0, 14, and 28 min to measure changes to bladder volumes, wall displacements, and center of gravity (COG) over time. RESULTS: The dominant source of bladder motion during imaging was bladder filling (up to 101% volume increase); rectal and small bowel movements were transient, with minimal impact. Bladder volume changes were similar for all participants. However for bladder cancer patients, wall displacements were larger (up to 58 mm), less symmetrical, and more variable compared with nondiseased control bladders. CONCLUSIONS: Significant and individualized intrafraction bladder wall displacements may occur during bladder RT delivery. This important source of inaccuracy should be incorporated into treatment planning and verification.
    Citation
    Assessment of bladder motion for clinical radiotherapy practice using cine-magnetic resonance imaging. 2009, 75 (3):664-71 Int. J. Radiat. Oncol. Biol. Phys.
    Journal
    International Journal of Radiation Oncology, Biology, Physics
    URI
    http://hdl.handle.net/10541/87685
    DOI
    10.1016/j.ijrobp.2008.11.040
    PubMed ID
    19473781
    Type
    Article
    Language
    en
    ISSN
    1879-355X
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.ijrobp.2008.11.040
    Scopus Count
    Collections
    All Christie Publications
    Christie Medical Physics and Engineering Research
    Clinical Oncology
    Academic Department of Radiation Oncology - ADRO

    entitlement

    Related articles

    • Assessing intra-fractional bladder motion using cine-MRI as initial methodology for Predictive Organ Localization (POLO) in radiotherapy for bladder cancer.
    • Authors: Mangar SA, Scurr E, Huddart RA, Sohaib SA, Horwich A, Dearnaley DP, Khoo VS
    • Issue date: 2007 Nov
    • Prostate gland motion assessed with cine-magnetic resonance imaging (cine-MRI).
    • Authors: Ghilezan MJ, Jaffray DA, Siewerdsen JH, Van Herk M, Shetty A, Sharpe MB, Zafar Jafri S, Vicini FA, Matter RC, Brabbins DS, Martinez AA
    • Issue date: 2005 Jun 1
    • A cinematic magnetic resonance imaging study of milk of magnesia laxative and an antiflatulent diet to reduce intrafraction prostate motion.
    • Authors: Nichol AM, Warde PR, Lockwood GA, Kirilova AK, Bayley A, Bristow R, Crook J, Gospodarowicz M, McLean M, Milosevic M, Rosewall T, Jaffray DA, Catton CN
    • Issue date: 2010 Jul 15
    • Three-dimensional motion of liver tumors using cine-magnetic resonance imaging.
    • Authors: Kirilova A, Lockwood G, Choi P, Bana N, Haider MA, Brock KK, Eccles C, Dawson LA
    • Issue date: 2008 Jul 15
    • Intrafraction motion in patients with cervical cancer: The benefit of soft tissue registration using MRI.
    • Authors: Kerkhof EM, van der Put RW, Raaymakers BW, van der Heide UA, Jürgenliemk-Schulz IM, Lagendijk JJ
    • Issue date: 2009 Oct
    DSpace software (copyright © 2002 - 2023)  DuraSpace
    Quick Guide | Contact Us
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.