Extraskeletal myxoid chondrosarcoma with neuroendocrine differentiation: a pathologic, cytogenetic, and molecular study of a case with a novel translocation t(9;17)(q22;q11.2).
dc.contributor.author | Harris, Martin | |
dc.contributor.author | Coyne, John | |
dc.contributor.author | Tariq, M | |
dc.contributor.author | Eyden, Brian P | |
dc.contributor.author | Atkinson, M | |
dc.contributor.author | Freemont, Anthony J | |
dc.contributor.author | Varley, Jennifer | |
dc.contributor.author | Attwooll, C | |
dc.contributor.author | Telford, Nicholas | |
dc.date.accessioned | 2009-11-23T11:56:33Z | |
dc.date.available | 2009-11-23T11:56:33Z | |
dc.date.issued | 2000-07 | |
dc.identifier.citation | Extraskeletal myxoid chondrosarcoma with neuroendocrine differentiation: a pathologic, cytogenetic, and molecular study of a case with a novel translocation t(9;17)(q22;q11.2). 2000, 24 (7):1020-6 Am. J. Surg. Pathol. | en |
dc.identifier.issn | 0147-5185 | |
dc.identifier.pmid | 10895826 | |
dc.identifier.uri | http://hdl.handle.net/10541/86667 | |
dc.description.abstract | A case of extraskeletal myxoid chondrosarcoma (EMC) in which there was histochemical, immunohistochemical, and ultrastructural evidence of neuroendocrine differentiation is reported. Genetic investigations showed the recently described novel translocation t(9;17)(q22;q11.2) and associated fusion of the CHN and RBP56 genes, contrasting with the translocation t(9;22)(q22;q12) and EWS/CHN gene fusion found in the majority of EMCs. | |
dc.language.iso | en | en |
dc.subject | Cancer DNA | en |
dc.subject | Biological Tumour Markers | en |
dc.subject | Soft Tissue Cancer | en |
dc.subject.mesh | Buttocks | |
dc.subject.mesh | Cell Differentiation | |
dc.subject.mesh | Chondrosarcoma | |
dc.subject.mesh | Chromosomes, Human, Pair 17 | |
dc.subject.mesh | Chromosomes, Human, Pair 9 | |
dc.subject.mesh | Cytogenetics | |
dc.subject.mesh | Humans | |
dc.subject.mesh | Immunohistochemistry | |
dc.subject.mesh | In Situ Hybridization | |
dc.subject.mesh | Male | |
dc.subject.mesh | Middle Aged | |
dc.subject.mesh | Neurosecretory Systems | |
dc.subject.mesh | Procollagen | |
dc.subject.mesh | RNA, Messenger | |
dc.subject.mesh | RNA, Neoplasm | |
dc.subject.mesh | Silver Staining | |
dc.subject.mesh | Soft Tissue Neoplasms | |
dc.subject.mesh | Translocation, Genetic | |
dc.subject.mesh | Tumor Markers, Biological | |
dc.title | Extraskeletal myxoid chondrosarcoma with neuroendocrine differentiation: a pathologic, cytogenetic, and molecular study of a case with a novel translocation t(9;17)(q22;q11.2). | en |
dc.type | Article | en |
dc.contributor.department | Department of Histopathology, Christie Hospital, Manchester, UK. | en |
dc.identifier.journal | The American Journal of Surgical Pathology | en |
html.description.abstract | A case of extraskeletal myxoid chondrosarcoma (EMC) in which there was histochemical, immunohistochemical, and ultrastructural evidence of neuroendocrine differentiation is reported. Genetic investigations showed the recently described novel translocation t(9;17)(q22;q11.2) and associated fusion of the CHN and RBP56 genes, contrasting with the translocation t(9;22)(q22;q12) and EWS/CHN gene fusion found in the majority of EMCs. |