Extraskeletal myxoid chondrosarcoma with neuroendocrine differentiation: a pathologic, cytogenetic, and molecular study of a case with a novel translocation t(9;17)(q22;q11.2).
Authors
Harris, MartinCoyne, John
Tariq, M
Eyden, Brian P
Atkinson, M
Freemont, Anthony J
Varley, Jennifer
Attwooll, C
Telford, Nicholas
Affiliation
Department of Histopathology, Christie Hospital, Manchester, UK.Issue Date
2000-07
Metadata
Show full item recordAbstract
A case of extraskeletal myxoid chondrosarcoma (EMC) in which there was histochemical, immunohistochemical, and ultrastructural evidence of neuroendocrine differentiation is reported. Genetic investigations showed the recently described novel translocation t(9;17)(q22;q11.2) and associated fusion of the CHN and RBP56 genes, contrasting with the translocation t(9;22)(q22;q12) and EWS/CHN gene fusion found in the majority of EMCs.Citation
Extraskeletal myxoid chondrosarcoma with neuroendocrine differentiation: a pathologic, cytogenetic, and molecular study of a case with a novel translocation t(9;17)(q22;q11.2). 2000, 24 (7):1020-6 Am. J. Surg. Pathol.Journal
The American Journal of Surgical PathologyPubMed ID
10895826Type
ArticleLanguage
enISSN
0147-5185Related articles
- Extraskeletal myxoid chondrosarcoma with neuroendocrine differentiation: a case report with fine-needle aspiration biopsy, histopathology, electron microscopy, and cytogenetics.
- Authors: Domanski HA, Carlén B, Mertens F, Akerman M
- Issue date: 2003 Sep-Oct
- Molecular genetic characterization of the EWS/CHN and RBP56/CHN fusion genes in extraskeletal myxoid chondrosarcoma.
- Authors: Panagopoulos I, Mertens F, Isaksson M, Domanski HA, Brosjö O, Heim S, Bjerkehagen B, Sciot R, Dal Cin P, Fletcher JA, Fletcher CD, Mandahl N
- Issue date: 2002 Dec
- Skeletal and extraskeletal myxoid chondrosarcoma: a comparative clinicopathologic, ultrastructural, and molecular study.
- Authors: Antonescu CR, Argani P, Erlandson RA, Healey JH, Ladanyi M, Huvos AG
- Issue date: 1998 Oct 15
- Fusion of the RBP56 and CHN genes in extraskeletal myxoid chondrosarcomas with translocation t(9;17)(q22;q11).
- Authors: Panagopoulos I, Mencinger M, Dietrich CU, Bjerkehagen B, Saeter G, Mertens F, Mandahl N, Heim S
- Issue date: 1999 Dec 9
- Extraskeletal myxoid chondrosarcoma: a clinicopathologic, immunohistochemical, and molecular analysis of 18 cases.
- Authors: Okamoto S, Hisaoka M, Ishida T, Imamura T, Kanda H, Shimajiri S, Hashimoto H
- Issue date: 2001 Oct