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    Faslodex (ICI 182780). an oestrogen receptor downregulator.

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    Authors
    Howell, Anthony
    Affiliation
    CRC Department of Medical Oncology, Christie Hospital NHS Trust, M20 4BX, Manchester, UK. maria.parker@christie-tr.nwest.nhs.uk
    Issue Date
    2000-09
    
    Metadata
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    Abstract
    Anti-oestrogen therapy, tamoxifen in particular, has revolutionised the treatment of breast cancer. However, the partial agonist activity of tamoxifen is associated with an increased risk of endometrial cancer and the acquisition by patients of tamoxifen-resistance. In an attempt overcome these negative aspects of tamoxifen therapy, 'pure' anti-oestrogens have been developed and are currently being investigated for the treatment of breast cancer.
    Citation
    Faslodex (ICI 182780). an oestrogen receptor downregulator. 2000, 36 Suppl 4:S87-8 Eur. J. Cancer
    Journal
    European Journal of Cancer
    URI
    http://hdl.handle.net/10541/86514
    DOI
    10.1016/S0959-8049(00)00241-0
    PubMed ID
    11056334
    Type
    Article
    Language
    en
    ISSN
    0959-8049
    ae974a485f413a2113503eed53cd6c53
    10.1016/S0959-8049(00)00241-0
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