Affiliation
Cancer Research Campaign Gene Therapy Group, Paterson Institute for Cancer Research, Manchester, UK.Issue Date
2001-12
Metadata
Show full item recordAbstract
Gene therapy has thus far promised much and delivered little. Much of this has been due to deficiencies in the reagents and methodologies employed in early clinical trials. Recent technological advances in vectors and haemopoietic stem cell manipulation, coupled with improved pre-clinical assays of gene transfer and expression in re-populating stem cells give cause for greater optimism. Here we review these advances and indicate areas requiring further development before clinical gene therapy in the haemopoietic system becomes a widely applicable treatment modality.Citation
Prospects for gene therapy using haemopoietic stem cells. 2001, 14 (4):823-34 Best Pract Res Clin HaematolJournal
Best Practice & Research. Clinical HaematologyDOI
10.1053/beha.2001.0175PubMed ID
11924924Type
ArticleLanguage
enISSN
1521-6926ae974a485f413a2113503eed53cd6c53
10.1053/beha.2001.0175