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    Prospects for gene therapy using haemopoietic stem cells.

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    Authors
    Fairbairn, Leslie J
    Ewing, Joanne
    Affiliation
    Cancer Research Campaign Gene Therapy Group, Paterson Institute for Cancer Research, Manchester, UK.
    Issue Date
    2001-12
    
    Metadata
    Show full item record
    Abstract
    Gene therapy has thus far promised much and delivered little. Much of this has been due to deficiencies in the reagents and methodologies employed in early clinical trials. Recent technological advances in vectors and haemopoietic stem cell manipulation, coupled with improved pre-clinical assays of gene transfer and expression in re-populating stem cells give cause for greater optimism. Here we review these advances and indicate areas requiring further development before clinical gene therapy in the haemopoietic system becomes a widely applicable treatment modality.
    Citation
    Prospects for gene therapy using haemopoietic stem cells. 2001, 14 (4):823-34 Best Pract Res Clin Haematol
    Journal
    Best Practice & Research. Clinical Haematology
    URI
    http://hdl.handle.net/10541/85580
    DOI
    10.1053/beha.2001.0175
    PubMed ID
    11924924
    Type
    Article
    Language
    en
    ISSN
    1521-6926
    ae974a485f413a2113503eed53cd6c53
    10.1053/beha.2001.0175
    Scopus Count
    Collections
    All Paterson Institute for Cancer Research

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