Characterisation of carotenoid radical cations in liposomal environments: interaction with vitamin C.
AffiliationSchool of Chemistry and Physics, Lennard-Jones Laboratories, Keele University, Staffordshire, UK.
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AbstractPulse radiolysis was used to generate the radical cations of beta-carotene and two xanthophylls, zeaxanthin and lutein, in unilamellar vesicles of dipalmitoylphosphatidyl choline. The rate constants for the reaction (repair) of these carotenoid radical cations with the water-soluble vitamin C were found to be similar (approximately 1x10(7) M(-1) s(-1)) for beta-carotene and zeaxanthin and somewhat lower (approximately 0.5x10(7) M(-1) s(-1)) for lutein. The results are discussed in terms of the microenvironment of the carotenoids and suggest that for beta-carotene, a hydrocarbon carotenoid, the radical cation is able to interact with a water-soluble species even though the parent hydrocarbon carotenoid is probably entirely in the non-polar region of the liposome.
CitationCharacterisation of carotenoid radical cations in liposomal environments: interaction with vitamin C. 2001, 60 (1):1-6 J. Photochem. Photobiol. B, Biol.
JournalJournal of Photochemistry and Photobiology. B, Biology
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