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    Changes in lipoprotein(a) levels measured by six kit methods during growth hormone treatment of growth hormone-deficient adults.

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    Authors
    Wieringa, Gilbert E
    Toogood, Andy
    Ryder, W David J
    Anderson, John
    Mackness, M
    Shalet, Stephen M
    Affiliation
    Departments of Biochemistry, Endocrinology, Medical Statistics, Christie Hospital NHS Trust, Wilmslow Road, Manchester, M20 4BX, UK.
    Issue Date
    2000-02
    
    Metadata
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    Abstract
    Lipoprotein(a) [Lp(a)], an independent risk factor for cardiovascular disease, has previously been reported to increase, decrease or show no change in growth hormone (GH)-deficient individuals receiving GH replacement. To assess whether these inconsistencies could be attributed to differences in immunoassay methods, Lp(a) was measured by six commercial kits at 0, 3, 6 and 9 months in nine GH-deficient individuals (median age 68.3 years, six male) during 9 months GH therapy. There was a significant rise in Lp(a) with the INCStar immunoturbidimetric (IT) method and the Mercodia enzyme linked immunosorbent assay (ELISA) (P
    Citation
    Changes in lipoprotein(a) levels measured by six kit methods during growth hormone treatment of growth hormone-deficient adults. 2000, 10 (1):14-9 Growth Horm. IGF Res.
    Journal
    Growth Hormone & IGF Research
    URI
    http://hdl.handle.net/10541/85465
    DOI
    10.1054/ghir.2000.0134
    PubMed ID
    10753588
    Type
    Article
    Language
    en
    ISSN
    1096-6374
    ae974a485f413a2113503eed53cd6c53
    10.1054/ghir.2000.0134
    Scopus Count
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    All Christie Publications

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