Changes in lipoprotein(a) levels measured by six kit methods during growth hormone treatment of growth hormone-deficient adults.
AffiliationDepartments of Biochemistry, Endocrinology, Medical Statistics, Christie Hospital NHS Trust, Wilmslow Road, Manchester, M20 4BX, UK.
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AbstractLipoprotein(a) [Lp(a)], an independent risk factor for cardiovascular disease, has previously been reported to increase, decrease or show no change in growth hormone (GH)-deficient individuals receiving GH replacement. To assess whether these inconsistencies could be attributed to differences in immunoassay methods, Lp(a) was measured by six commercial kits at 0, 3, 6 and 9 months in nine GH-deficient individuals (median age 68.3 years, six male) during 9 months GH therapy. There was a significant rise in Lp(a) with the INCStar immunoturbidimetric (IT) method and the Mercodia enzyme linked immunosorbent assay (ELISA) (P
CitationChanges in lipoprotein(a) levels measured by six kit methods during growth hormone treatment of growth hormone-deficient adults. 2000, 10 (1):14-9 Growth Horm. IGF Res.
JournalGrowth Hormone & IGF Research
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