An EMA negative, desmin positive malignant mesothelioma: limitations of immunohistochemistry?
AffiliationEast Lancashire Hospitals, UK. email@example.com
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AbstractHistopathologists in the current environment of medical negligence and litigation are more likely to use immunohistochemical investigations in their day-to-day practice to support their diagnosis and avoid future litigation. The caveat is that relying on immunohistochemistry is a double-edged sword and pathologists should be familiar with its limitations. We present a case of primary malignant peritoneal mesothelioma with an unusual immunohistochemical profile-desmin positive, EMA negative-and wish to highlight the importance of cautiously interpreting immunohistochemistry profiles when they do not fit the clinical history and histological appearance.
CitationAn EMA negative, desmin positive malignant mesothelioma: limitations of immunohistochemistry? 2009, 62 (7):651-2 J. Clin. Pathol.
JournalJournal of Clinical Pathology