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dc.contributor.authorRu, Yong-Xin
dc.contributor.authorEyden, Brian P
dc.contributor.authorLi, Qing-Hua
dc.contributor.authorMao, Bing-Yu
dc.contributor.authorLiu, En-Bin
dc.contributor.authorPang, Tian-Xiang
dc.date.accessioned2009-11-02T13:18:05Z
dc.date.available2009-11-02T13:18:05Z
dc.date.issued2009
dc.identifier.citationMyofibroblast transformation in metastatic extramedullary chronic myeloid leukemia: a case report. 2009, 33 (3):136-40 Ultrastruct Patholen
dc.identifier.issn1521-0758
dc.identifier.pmid19479654
dc.identifier.doi10.1080/01913120902786961
dc.identifier.urihttp://hdl.handle.net/10541/85165
dc.description.abstractPrimary and metastatic carcinomas have a reactive stroma characterized by many myofibroblasts. These cells have also been documented in nonepithelial malignancies, such as sarcomas, malignant melanoma, and lymphoid tumors but in generally far fewer numbers. In non-Hodgkin's lymphoma, Hodgkin's disease, and leukemia, myofibroblasts are rather rarely documented. In particular, there appear to be no reports of myofibroblasts in either primary bone-marrow/peripheral blood leukemia or secondary deposits of leukemia. In this paper, a case of a relapsed chronic myeloid leukemia appearing in an inguinal lymph node is described, containing many myofibroblasts. The case is detailed and presented with a discussion on the role of myofibroblasts in the progression of nonepithelial cancers.
dc.language.isoenen
dc.subjectCancerous Cell Transformationen
dc.subjectMyelogenic Leukaemiaen
dc.subject.meshCell Transformation, Neoplastic
dc.subject.meshDisease Progression
dc.subject.meshFemale
dc.subject.meshFibroblasts
dc.subject.meshHumans
dc.subject.meshLeukemia, Myelogenous, Chronic, BCR-ABL Positive
dc.subject.meshLymph Nodes
dc.subject.meshMicroscopy, Electron, Transmission
dc.subject.meshMiddle Aged
dc.subject.meshMyocytes, Smooth Muscle
dc.subject.meshOrganelles
dc.subject.meshRecurrence
dc.titleMyofibroblast transformation in metastatic extramedullary chronic myeloid leukemia: a case report.en
dc.typeArticleen
dc.contributor.departmentInstitute of Hematology & Blood Diseases Hospital, Peking Union Medical College, Tianjin, China.en
dc.identifier.journalUltrastructural Pathologyen
html.description.abstractPrimary and metastatic carcinomas have a reactive stroma characterized by many myofibroblasts. These cells have also been documented in nonepithelial malignancies, such as sarcomas, malignant melanoma, and lymphoid tumors but in generally far fewer numbers. In non-Hodgkin's lymphoma, Hodgkin's disease, and leukemia, myofibroblasts are rather rarely documented. In particular, there appear to be no reports of myofibroblasts in either primary bone-marrow/peripheral blood leukemia or secondary deposits of leukemia. In this paper, a case of a relapsed chronic myeloid leukemia appearing in an inguinal lymph node is described, containing many myofibroblasts. The case is detailed and presented with a discussion on the role of myofibroblasts in the progression of nonepithelial cancers.


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