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    Myofibroblast transformation in metastatic extramedullary chronic myeloid leukemia: a case report.

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    Authors
    Ru, Yong-Xin
    Eyden, Brian P
    Li, Qing-Hua
    Mao, Bing-Yu
    Liu, En-Bin
    Pang, Tian-Xiang
    Affiliation
    Institute of Hematology & Blood Diseases Hospital, Peking Union Medical College, Tianjin, China.
    Issue Date
    2009
    
    Metadata
    Show full item record
    Abstract
    Primary and metastatic carcinomas have a reactive stroma characterized by many myofibroblasts. These cells have also been documented in nonepithelial malignancies, such as sarcomas, malignant melanoma, and lymphoid tumors but in generally far fewer numbers. In non-Hodgkin's lymphoma, Hodgkin's disease, and leukemia, myofibroblasts are rather rarely documented. In particular, there appear to be no reports of myofibroblasts in either primary bone-marrow/peripheral blood leukemia or secondary deposits of leukemia. In this paper, a case of a relapsed chronic myeloid leukemia appearing in an inguinal lymph node is described, containing many myofibroblasts. The case is detailed and presented with a discussion on the role of myofibroblasts in the progression of nonepithelial cancers.
    Citation
    Myofibroblast transformation in metastatic extramedullary chronic myeloid leukemia: a case report. 2009, 33 (3):136-40 Ultrastruct Pathol
    Journal
    Ultrastructural Pathology
    URI
    http://hdl.handle.net/10541/85165
    DOI
    10.1080/01913120902786961
    PubMed ID
    19479654
    Type
    Article
    Language
    en
    ISSN
    1521-0758
    ae974a485f413a2113503eed53cd6c53
    10.1080/01913120902786961
    Scopus Count
    Collections
    All Christie Publications
    Radiology

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