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dc.contributor.authorShilling, V
dc.contributor.authorJenkins, Valerie A
dc.contributor.authorFallowfield, Lesley J
dc.contributor.authorHowell, Anthony
dc.date.accessioned2009-10-13T08:37:52Z
dc.date.available2009-10-13T08:37:52Z
dc.date.issued2001-12
dc.identifier.citationThe effects of oestrogens and anti-oestrogens on cognition. 2001, 10 (6):484-91 Breasten
dc.identifier.issn0960-9776
dc.identifier.pmid14965628
dc.identifier.doi10.1054/brst.2001.0311
dc.identifier.urihttp://hdl.handle.net/10541/84118
dc.description.abstractRecent research suggests that oestrogen may play an important role in cognition. Epidemiological and experimental studies of hormone replacement therapy in post-menopausal women suggest that oestrogen may be important to verbal memory in particular, as well as other cognitive functions such as attention and processing speed. Some studies have also suggested that HRT may have a beneficial effect for Alzheimer's disease, both in the prevention or delay of onset and that it is also of therapeutic benefit to patients in whom the disease is established. The use of selective oestrogen receptor modulators (SERMs) and other hormonal therapies for the treatment of breast cancer is common, yet few studies have examined the possible cognitive effects of this form of treatment. Several studies have shown cognitive decline in women receiving treatment for breast cancer, but the focus has been on the effects of chemotherapy. Further confusion has resulted from the diverse methodologies used in the existing literature. A pilot study to develop a suitable cognitive battery of tests for the evaluation of cognitive function in women receiving hormonal therapy for the treatment or prevention of breast cancer is introduced.
dc.language.isoenen
dc.subjectOestrogenen
dc.subjectHormone Replacement Therapyen
dc.subjectCognitionen
dc.subjectHormonal Therapiesen
dc.subjectBreast Canceren
dc.titleThe effects of oestrogens and anti-oestrogens on cognition.en
dc.typeArticleen
dc.contributor.departmentCRC Psychosocial Oncology Group, University of Sussex, UK.en
dc.identifier.journalBreasten
html.description.abstractRecent research suggests that oestrogen may play an important role in cognition. Epidemiological and experimental studies of hormone replacement therapy in post-menopausal women suggest that oestrogen may be important to verbal memory in particular, as well as other cognitive functions such as attention and processing speed. Some studies have also suggested that HRT may have a beneficial effect for Alzheimer's disease, both in the prevention or delay of onset and that it is also of therapeutic benefit to patients in whom the disease is established. The use of selective oestrogen receptor modulators (SERMs) and other hormonal therapies for the treatment of breast cancer is common, yet few studies have examined the possible cognitive effects of this form of treatment. Several studies have shown cognitive decline in women receiving treatment for breast cancer, but the focus has been on the effects of chemotherapy. Further confusion has resulted from the diverse methodologies used in the existing literature. A pilot study to develop a suitable cognitive battery of tests for the evaluation of cognitive function in women receiving hormonal therapy for the treatment or prevention of breast cancer is introduced.


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