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    The effects of oestrogens and anti-oestrogens on cognition.

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    Authors
    Shilling, V
    Jenkins, Valerie A
    Fallowfield, Lesley J
    Howell, Anthony
    Affiliation
    CRC Psychosocial Oncology Group, University of Sussex, UK.
    Issue Date
    2001-12
    
    Metadata
    Show full item record
    Abstract
    Recent research suggests that oestrogen may play an important role in cognition. Epidemiological and experimental studies of hormone replacement therapy in post-menopausal women suggest that oestrogen may be important to verbal memory in particular, as well as other cognitive functions such as attention and processing speed. Some studies have also suggested that HRT may have a beneficial effect for Alzheimer's disease, both in the prevention or delay of onset and that it is also of therapeutic benefit to patients in whom the disease is established. The use of selective oestrogen receptor modulators (SERMs) and other hormonal therapies for the treatment of breast cancer is common, yet few studies have examined the possible cognitive effects of this form of treatment. Several studies have shown cognitive decline in women receiving treatment for breast cancer, but the focus has been on the effects of chemotherapy. Further confusion has resulted from the diverse methodologies used in the existing literature. A pilot study to develop a suitable cognitive battery of tests for the evaluation of cognitive function in women receiving hormonal therapy for the treatment or prevention of breast cancer is introduced.
    Citation
    The effects of oestrogens and anti-oestrogens on cognition. 2001, 10 (6):484-91 Breast
    Journal
    Breast
    URI
    http://hdl.handle.net/10541/84118
    DOI
    10.1054/brst.2001.0311
    PubMed ID
    14965628
    Type
    Article
    Language
    en
    ISSN
    0960-9776
    ae974a485f413a2113503eed53cd6c53
    10.1054/brst.2001.0311
    Scopus Count
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